The S-Nitrosylation of Parkin Attenuated the Ubiquitination of Divalent Metal Transporter 1 in MPP+-Treated SH-SY5Y Cells

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To elucidate the role of S-nitrosylated parkin and divalent metal transporter 1 in Parkinson’s disease, SH-SY5Y cells were transfected with parkin, being treated with S-nitrosoglutathione and 1-methyl-4-phenylpyridinium (MPP+).
[Scientific Reports]
Zhong, Y., Li, X., Du, X., Bi, M., Ma, F., Xie, J., & Jiang, H. (2020). The S-nitrosylation of parkin attenuated the ubiquitination of divalent metal transporter 1 in MPP + -treated SH-SY5Y cells. Scientific Reports, 10(1), 15542. https://doi.org/10.1038/s41598-020-72630-2 Cite
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