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[Nature Communications] The authors established a doxycycline-titratable system for genetic induction of permanent intratumor expression of KDM5B and screened for chemical agents that phenocopy this effect.

[Cell Biology and Toxicology] In vitro, the effect of the combination regimen of vemurafenib and b-AP15 on vem-sensitive and vem-resistant melanoma has been investigated by wound healing, colony formation, transwell invasion assay, flow cytometry, lysosome staining, and ROS detection.

[iScience] Researchers succeeded in visualizing collagen-producing cells and produced collagen using the axolotl skin, which is highly transparent. The visualized dermal collagen had a lattice-like structure.

[Cell Death & Disease] The polarization of M2 macrophages transduced by the acid-sensing ion channel 3 (ASIC3)-macrophage colony-stimulating factor (M-CSF) signal promoted the differentiation of fibroblasts into myofibroblasts through transforming growth factor β1 (TGF-β1), thereby producing an ASIC3-M-CSF-TGF-β1 positive feedback loop.

[Pigment Cell & Melanoma Research] The purpose of this study was to standardize 3-D imaging and quantification for the evaluation of epidermal melanocytes.

[Neoplasia] The characteristics of non-melanoma carcinoma is discussed, describing the main existing treatments, together with the contribution of lipid delivery systems as an innovative approach to increase the effectiveness of topical therapies for non-melanoma carcinomas.