Mesenchymal Cell News

Mesenchymal Cell News is an online resource that delivers updates on the latest research in the mesenchymal stem cell field.

Subscribe|Follow Us On

ADMSC-Derived Exosomes Promote Diabetic Wound Healing by Inhibiting Neutrophil Extracellular Traps Formation through Delivering Mir-92a-1-5p

February 3, 2026

[Archives of Biochemistry and Biophysics] Scientists showed the healing process of skin wounds in diabetic rats was notably delayed, but this delay was mitigated by the administration of adipose-derived MSC-derived exosomes.

Conditioned Medium from Human Adipose-Derived Mesenchymal Stromal Cells Can Modulate Cell Migration and Morphology of Keratinocytes In Vitro

February 3, 2026

[Human Cell] Researchers produced conditioned medium using primary cultures from human adipose-derived MSCs. This medium was used as treatment in a culture of keratinocyte cell line from adult human skin to investigate the modulation of their dynamics.

Ectopic Endometrial Mesenchymal Stem Cell-Derived Exosomal Mir-4466 Promotes Angiogenesis by Targeting RUNX1 in Adenomyosis

February 3, 2026

[Biochemistry and Biophysics Reports] The authors investigated the pro-angiogenic role and potential mechanisms of ectopic endometrial MSC-derived exosomes.

Mesenchymal Stem Cells Alleviate Experimental Cerebral Malaria Disease Severity by Inducing RoRγT+ Foxp3+ T Regulatory (Tr 17) Cells and Modulating the Dysregulated Th17/Treg Axis

February 3, 2026

[Cell Death Discovery] The authors investigated the therapeutic potential of MSCs in managing the excess proinflammatory response and maintaining immune homeostasis in Plasmodium berghei ANKA infected C57BL/6 mice, an experimental cerebral malaria disease model.

Mesenchymal Stem Cell-Derived Extracellular Matrix for Musculoskeletal Tissue Regeneration

February 3, 2026

[Communications Biology] The authors summarize the preparation methods and composition of MSC-derived extracellular matrix, its effects on regulating cell behavior, and its applications in bone, cartilage, muscle, nerve, and blood vessel repair.

Fndc5 Modification Optimizes the Therapeutic Effect of Rat MSCs on Sepsis-Induced ALI/ARDS via Activating the PI3K/AKT Signaling Pathway

January 29, 2026

[Stem Cell Research & Therapy] Fibronectin type III domain-containing protein 5 (Fndc5) modification significantly increased the retention rate of MSCs in sepsis-induced acute lung injury murine model while augmenting their in vitro proliferation and migration potential.

Mesenchymal Stem Cells Attenuate Systemic Sclerosis Related Lung Fibrosis by Inhibiting T Follicular Helper Cells in Tertiary Lymphoid Structure

January 29, 2026

[Arthritis Research & Therapy] T follicular helper cells, which could promote fibrosis both in vivo and in vitro, played a pivotal role in the pathogenesis of systemic sclerosis related interstitial lung disease.

Cellular Iron Flux Measurement by Micromagnetic Resonance Relaxometry As a Critical Quality Attribute of Mesenchymal Stromal Cells

January 29, 2026

[Stem Cells Translational Medicine] Researchers identified iron homeostasis as a potential chondrogenic-associated critical quality attribute of MSCs.

Human Amniotic Mesenchymal Stromal Cells Promote Bone Regeneration via Regulating Ameloblastoma-Derived-Bone Marrow Mesenchymal Cells Crosstalk and Autophagy in Ameloblastoma Microenvironment

January 29, 2026

[Tissue Engineering and Regenerative Medicine] Scientists analyzed the role of human amniotic MSCs (HAMSCS) in the cross-talk between mesenchymal ameloblastoma-derived cells, human bone marrow MSCs, and HAMSCs.

Validation of a Novel Genomic Biomarker of Mesenchymal Stem Cell Scalability and Implications of Genotype Status on Cellular Senescence Phenotypes

January 28, 2026

[Scientific Reports] Scientists investigated the role of GSTT1 genotype in bone marrow-derived-MSC senescence and proliferation.

Landmark FDA Move: First Quality Control Protocol for Mesenchymal Stromal Cells (MSCs) Sets New Therapeutic Standard

January 28, 2026

[Tasly Pharmaceuticals] In a landmark move for the cell therapy industry, a Device Master File describing the first dedicated quality control standard for MSCs was accepted by the US FDA.

MEDIPOST Inc. Announces $140 Million in Funding to Accelerate Late-Stage Clinical Development

January 19, 2026

MEDIPOST, Inc. announced that its parent company, MEDIPOST Co., Ltd., has closed on $140 million in funding. The investment will accelerate the company’s Phase...

Mesenchymal Cell News covers topics such as the isolation, identification, and culturing conditions of mesenchymal stem cells, as well as their cellular characterization, behavior and differentiation capacities. We also include research that focuses on identifying tissue sources of mesenchymal stem cells and their potential therapeutic applications in regenerative medicine and cellular therapies.