 | | Vol. 8.25 – 22 August, 2022 |
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| By combining single-cell and spatial transcriptomics on human basal cell carcinomas, researchers defined the cellular contributors of tumor progression.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| Elevated platelet-derived growth factor receptor α (PDGFRα) signaling increased proliferation but unexpectedly delayed the fibroblast-to-myofibroblast transition, suggesting that PDGFRα must be downregulated for myofibroblast differentiation.
[Cell Reports] |
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| Scientists identified the basal cell adhesion molecule, a β1 integrin coreceptor, as a novel regulator of epidermal morphogenesis.
[PLoS Biology] |
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| Investigators evaluated the effect of a conjugated angiopoietin-1 derived peptide hydrogel on human skin wound healing using a mouse xenograft model.
[Scientific Reports] |
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| Using neural networks, researchers predicted senescence from the nuclear morphology of human fibroblasts with up to 95% accuracy, and investigated murine astrocytes, murine neurons, and fibroblasts with premature aging in culture.
[Nature Aging] |
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| Scientists developed a therapeutic strategy for melanoma using bromosporine, a bromodomain inhibitor. Bromosporine monotherapy produced significant anti-tumor effects against established melanoma cell lines and patient-derived xenografts.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| The authors designed a dissolvable microneedles patch that was loaded with conditioned media derived from hypoxia-pretreated mesenchymal stem cells, which contained elevated HIF-1α.
[Journal of Controlled Release] |
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| Researchers demonstrated that a highly conserved interferon-γ-activated inhibitor of translation (GAIT)-like motif located upstream of the GU-rich elements of HuR major polyadenylation site, interacts with constituents of the GAIT complex and affects HuR post-transcriptional expression regulation.
[Biochemical and Biophysical Research Communications] |
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| The author discusses the plasticity and function of adipocytes to tissue repair and fibrosis in four tissues: skin, heart, skeletal muscle, and mammary gland.
[Current Opinion in Genetics & Development] |
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| This review explores the role of nucleic acid (NA) based therapeutics in various stages of wound healing and provides an update on the most recent findings in the development of NA-based nanomedicine and biomaterials.
[International Journal of Biological Macromolecules] |
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| A new study found that more melanomas in advanced stages and with aggressive features were diagnosed during the pandemic, suggesting COVID-19 shutdowns caused a delay in the diagnosis.
[The World Link] |
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| International Space Station astronauts took turns investigating how spaceflight conditions, such as weightlessness and radiation, affect genetic expressions that occur during the healing process.
[NASA] |
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| October 20 – 21, 2022
Turin, Italy |
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| | Helmholtz Munich – Munich, Germany |
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| | National Research Council Canada – Toronto, Ontario, Canada |
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| | Lehigh University – Bethlehem, Pennsylvania, Untied States |
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| | NIH National Cancer Institute – Bethesda, Maryland, United States |
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| | Virginia Commonwealth University – Richmond, Virginia, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
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Pancreatic Cell News
Prostate Cell News
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