| Vol. 7.29 – 22 August, 2022 |
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| The authors developed a droplet microfluidics–based mitochondrial transfer technique that could achieve high-efficiency and high-throughput quantitative mitochondrial transfer to single cells. [Science Advances] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers established a murine model of pregestational diabetes to uncover the transcriptional responses in key cell-types of the developing heart exposed to maternal hyperglycemia. [Communications Biology] |
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| Scientists demonstrated the existence of a functionally independent calcium signaling compartment in the cardiac myocyte regulating hypertrophy and provided a premise for targeting mAKAPβ signalosomes to prevent selectively cardiac hypertrophy in disease. [Journal of Molecular and Cellular Cardiology] |
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| Investigators found that serum response factor (SRF) directly controlled the cardiac expression of miR210. [Biochemical and Biophysical Research Communications] |
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| In vitro, Acsl6 overexpression partially attenuated ISO-induced cardiomyocyte hypertrophy and increases in hypertrophic markers. [Journal of Cardiovascular Pharmacology] |
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| Researchers investigated the mechanism of the lysine-specific histone demethylase 1A (KDM1A) on cardiomyocyte apoptosis after myocardial ischemia-reperfusion injury. [Peerj] |
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| Differentiated C2C12 myotubes were treated with lipopolysaccharide to induce activation of the nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3 (NLRP3) inflammasome with and without MCC950, a pharmacological inhibitor of NLRP3-induced IL-1β production. [Journal of Cachexia Sarcopenia and Muscle] |
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| Scientists identified NID-1 among the adipose tissue secreted factors impairing myogenic potential of human myoblasts and murine muscle stem cells in vitro. [Matrix Biology] |
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| Researchers investigated the role of platelet-derived growth factor receptors β (PDGFRβ) lineage cells in skeletal muscle during aging by using Cre/loxP lineage tracing technology. [Stem Cell Research & Therapy] |
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| | The authors investigated the dynamics of vascular smooth muscle cells (VSMCs) clone formation using confocal microscopy and single cell transcriptomics in VSMC-lineage-traced animal models. [Cardiovascular Research] |
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| Rat bone marrow mesenchymal stem cells and smooth muscle cell were obtained from the bone marrow and bladder of Sprague-Dawley rats, respectively. Flow cytometry and multilineage differentiation were performed to assess the characteristics of these cells. [Disease Markers] |
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| Scientists reviewed the mechanisms of cardiomyocyte (CM) differentiation during development and from regenerative stem cells with a focus on the involvement of microRNAs in the process, putting in perspective their negative gene regulation as a main modifier of effective CM regeneration in the adult heart. [Clinical Science] |
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| Dr. Michelle Collins was recently awarded a Natural Sciences and Engineering Research Council of Canada Discovery Grant of $185,000 over five years to pursue the deeper question of how calcium moves through the cell and what controls that flux. [University of Saskatchewan] |
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| The National Institutes of Health (NIH) has awarded a five-year, $11.2 million to Dr. Jianyi “Jay” Zhang and colleagues to study how to restore the dead tissue from a heart attack, through the growth of new heart muscle cells. [University of Alabama at Birmingham] |
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| February 5 – 8, 2022 Keystone, Colorado, United States |
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| University of British Columbia – Vancouver, British Columbia, Canada |
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| Duke University – Durham, North Carolina, United States |
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| University of Alberta – Edmonton, Alberta, Canada |
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| Darmstadt University of Technology – Darmstadt, Germany |
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| Nationwide Children’s Hospital – Columbus, Ohio, United States |
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