Innate Immune Cell Response to Host-Parasite Interaction in a Human Intestinal Tissue Microphysiological System

The authors developed a human microphysiological system of intestinal tissue to evaluate parasite-immune–specific interactions during infection, which integrated primary intestinal epithelial cells and immune cells to investigate the role of innate immune cells during epithelial infection by the protozoan parasite, Toxoplasma gondii.