Post-Transplant Cyclophosphamide Alters Immune Signatures and Leads to Impaired T Cell Reconstitution in Allogeneic Hematopoietic Stem Cell Transplant

Using blood samples from patients who underwent allogeneic hematopoietic stem cell transplantation under regimens containing post-transplant cyclophosphamide (PTCy) versus those who received no PTCy, researchers examined the impact of PTCy on the post-transplant immune response.