Single-Cell RNA-Seq of a Soft-Tissue Sarcoma Model Reveals the Critical Role of Tumor-Expressed MIF in Shaping Macrophage Heterogeneity

Scientists employed single-cell RNA sequencing to characterize the immune composition of an undifferentiated pleiomorphic sarcoma mouse model, showing that macrophages in the sarcoma mass exhibit distinct activation states.
[Cell Reports]
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