KCNQ1-Deficient and KCNQ1-Mutant Human Embryonic Stem Cell-Derived Cardiomyocytes for Modeling QT Prolongation

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Bob
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KCNQ1 was knocked out in hESC H9 line using the CRISPR/cas9 system. KCNQ1-deficient and KCNQ1-mutant hESCs were differentiated into cardiomyocytes through a chemically defined differentiation protocol.
[Stem Cell Research & Therapy]
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