The Multifaceted Role of LRRK2 in Parkinson’s Disease: From Human iPSC to Organoids

The authors discuss the use of hiPSCs as a model for Parkinson’s disease pathology and research on the Leucine-Rich Repeat Kinase 2 (LRRK2) function in both neuronal and immune cells, together with reviewing the recent advances in 3D organoid models and microfluidics.