Sequestration of Gut Pathobionts in Intraluminal Casts, a Mechanism To Avoid Dysregulated T Cell Activation by Pathobionts

Mechanistic exploration revealed that the capsule-less mutants remained able to induce species-specific immunoglobulin A and were highly IgA-coated. They could still trigger myeloid cells, and more effectively damaged epithelial cells in vitro.