NDR1 Activates CD47 Transcription by Increasing Protein Stability and Nuclear Location of ASCL1 to Enhance Cancer Stem Cell Properties and Evasion of Phagocytosis in Small Cell Lung Cancer

The authors explored the function of NDR1 in the control of CSC properties in small cell lung cancer (SCLC), and found that NDR1 promoted ASCL1 expression to enhance NDR1-promoted CSC properties and evasion of phagocytosis in SCLC cells.