Noxa and Mcl-1 Expression Influence the Sensitivity to BH3-Mimetics That Target Bcl-xL in Patient-Derived Glioma Stem Cells

Researchers determined that the most abundantly expressed anti-apoptotic Bcl-2 family members, Bcl-xL and Mcl-1, were the most relevant in regulating patient-derived glioma stem cell survival.