A Conserved Population of MHC II-Restricted, Innate-Like, Commensal-Reactive T Cells in the Gut of Humans and Mice

The conserved cell population was abundant in the human and murine colon, and endowed with polyfunctional effector properties spanning classic Th1- and Th17-cytokines, cytotoxic molecules, and regulators of epithelial homeostasis.