Impairment of FOXM1 Expression in Mesenchymal Cells from Patients with Myeloid Neoplasms, De Novo and Therapy-Related, May Compromise Their Ability to Support Hematopoiesis

Scientists investigated expression of the FOXM1 gene in bone marrow mesenchymal stem cells (BM-MSCs) isolated from patients with myelodysplastic syndromes and AML and compared it to BM-MSCs isolated from healthy donors.