SARS-CoV-2-Mediated Lung Edema and Replication Are Diminished by Cystic Fibrosis Transmembrane Conductance Regulator Modulators

Scientists found that the PDZ-binding motifs of SARS-CoV, MERS-CoV, and SARS-CoV-2 were virulence factors required for optimal replication and the generation of alveolar edema.