Bone Marrow Mesenchymal Stem Cells’ Osteogenic Potential: Superiority or Non-Superiority to Other Sources of Mesenchymal Stem Cells?
The authors review the specific potential of bone marrow MSCs and compare their osteogenic potential with other types of MSCs, and discuss the future directions of bone marrow MSCs as a source for cell therapy.
[British Journal of Cancer] The immunoproteasome subunit LMP7 was silenced by using gene knockout or inhibited by the epoxyketone inhibitor ONX 0914 in a mouse castration-resistant prostate cancer (CRPC) tumor graft model and in interferon-γ-pretreated human CRPC cell lines in vitro.
[British Journal of Cancer] 582 mCRPC patients undergoing first-line abiraterone therapy from four institutions were sorted by three phases: discovery, training, and validation.
[International Journal of Radiation Oncology*Biology*Physics] Researchers performed an international multi-institutional retrospective study of 277 men with metachronous oligometastatic castration-sensitive prostate cancer who underwent targeted DNA sequencing of their primary/metastatic tumor.