Fructose-1,6-Bisphosphatase 1 Dephosphorylates IκBα and Suppresses Colorectal Tumorigenesis

Scientists revealed a previously unrecognized role of fructose 1,6-bisphosphate (FBP1) as a protein phosphatase and established the critical role of FBP1-mediated IκBα dephosphorylation in colorectal tumorigenesis.