SERS Microsensors for pH Measurements in the Lumen and ECM of Stem Cell Derived Human Airway Organoids

Scientists demonstrated that by mixing surface enhanced Raman scattering microsensors (SERS-MS) into the extracellular matrix of airway organoid cultures, the probes could be engulfed by expanding organoids, and reported on local pH in the organoid lumen and extracellular matrix.