WDR3 Promotes Stem Cell-Like Properties in Prostate Cancer by Inhibiting USF2-Mediated Transcription of RASSF1A

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WD repeat domain 3 (WDR3) was negatively correlated with USF2, which was degraded by promoting ubiquitination of USF2, and USF2 interacted with promoter region-binding elements of RASSF1A to depress prostate cancer stemness and growth.
[The Journal Of Gene Medicine]
Abstract