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e.g. organoids

N-Acetylneuraminic Acid Links Immune Exhaustion and Accelerated Memory Deficit in Diet-Induced Obese Alzheimer’s Disease Mouse Model

In an obese Alzheimer’s disease mouse model, hippocampal cells displayed only minor diet-related transcriptional changes, whereas the splenic immune landscape exhibited aging-like CD4+ T-cell deregulation.
[Nature Communications]
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