LncRNA HOXB-AS4 Promotes Proliferation and Migration of Colorectal Cancer via the miR-140-5p/hdac7 Axis

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Researchers found that HOXB-AS4 was markedly upregulated in tumor tissues compared to precancerous tissues. Loss-of-function assays in HT29 and SW480 cells confirmed that knockdown of HOXB-AS4 inhibited proliferation, migration, and promoted apoptosis.
[Biotechnology and Genetic Engineering Reviews]
Abstract