Skin Aging from the Perspective of Dermal Fibroblasts: The Interplay between the Adaptation to the Extracellular Matrix Microenvironment and Cell Autonomous Processes

Scientists review how dermal aging involves a feed‐forward process that reinforces the aged dermal fibroblast phenotype and promotes age‐related dermal extracellular matrix deterioration, and discuss the expression of the aged dermal fibroblast phenotype.