Genetic Mapping Reveals Pou2af2/OCA-T1–Dependent Tuning of Tuft Cell Differentiation and Intestinal Type 2 Immunity

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Researchers exploited differences between inbred mouse strains to identify an epithelium-intrinsic mechanism that regulated tuft cell differentiation and tunes innate type 2 immunity in the small intestine.
[Science Immunology]
Abstract