Remodeling of the Immune and Stromal Cell Compartment by PD-1 Blockade in Mismatch Repair-Deficient Colorectal Cancer

Researchers utilized single-cell RNA sequencing to investigate the dynamics of immune and stromal cells in 19 patients with mismatch repair-deficient and microsatellite instability-high colorectal cancers who received neoadjuvant PD-1 blockade.