SARS-CoV-2 N Protein Enhances the Anti-Apoptotic Activity of MCL-1 To Promote Viral Replication

Scientists found SARS-CoV-2 virus-like particles (trVLP) suppressed cell apoptosis, but the trVLP lacking N protein did not. Further study verified that N protein repressed cell apoptosis in cultured cells, human lung organoids, and mice.