Rad1 Attenuates DNA Double-Strand Breaks and Cell Cycle Arrest in Type II Alveolar Epithelial Cells of Rats With Bronchopulmonary Dysplasia

The accumulation of DNA double-strand breaks in primary type II alveolar epithelial cells may be an important cause of alveolar growth arrest associated with bronchopulmonary dysplasia (BPD). Rad1 could be an effective target for intervention to improve this arrest in lung development associated with BPD.