GLP-1 Receptor Agonist Protects Palmitate-Induced Insulin Resistance in Skeletal Muscle Cells by Up-Regulating sestrin2 to Promote Autophagy

Scientists investigated whether liraglutide could effectively reduce insulin resistance (IR) by regulating sestrin2 (SESN2) expression in L6 rat skeletal muscle cells by examining its interactions with SESN2, autophagy, and IR.