MTAP-ANRIL Gene Fusion Promotes Melanoma Epithelial-Mesenchymal Transition-Like Process by Activating the JNK and p38 Signaling Pathways

Scientists found that MTAP-ANRIL gene fusion downregulated the expression of wild-type MTAP and promoted epithelial-mesenchymal transition-like process through the activation of JNK and p38 MAPKs in vitro and in vivo.