MCK2-Mediated MCMV Infection of Macrophages and Virus Dissemination to the Salivary Gland Depends on MHC Class I Molecules

Using a CRISPR screen, investigators identified that murine cytomegalovirus (MCMV)-encoded chemokine 2 (MCK2)-dependent infection required MHC class Ia/β-2-microglobulin expression.