An Antioxidant Ameliorates Allergic Airway Inflammation by Inhibiting HDAC 1 via HIF-1α/VEGF Axis Suppression in Mice

Scientists investigated possible pathways by which curcumin and sodium butyrate may minimize asthma pathogenesis via histone deacetylase 1 inhibition. Balb/c mice were exposed to Ovalbumin to establish an allergic asthma model followed by pretreatment of curcumin and sodium butyrate through intranasal route.