NewslettersExtracellular Matrix NewsMesenchymal Cell NewsDiscovery and Targeting of a Noncanonical Mechanism of Sarcoma Resistance to ADI-PEG20 Mediated by the MicroenvironmentBy lbeveridge - June 27, 20230188Tumor initiation and growth rates were measured for a spontaneous Ass1 knockout murine sarcoma model. Tumor cell lines were generated, and resistance to arginine deprivation therapy was studied in vitro and in vivo.[Clinical Cancer Research]Abstract