MLK4 Promotes Glucose Metabolism in Lung Adenocarcinoma Through CREB-Mediated Activation of Phosphoenolpyruvate Carboxykinase and Is Regulated by KLF5

Investigators showed that MLK4 was overexpressed in a significant subset of lung adenocarcinoma, associated with a worse prognosis, and exerted an oncogenic function in vitro and in vivo.