Natural Compound Fraxinellone Ameliorates Intestinal Fibrosis in Mice via Direct Intervention of HSP47-Collagen Interaction in the Epithelium

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Researchers investigated the therapeutic potential and underlying mechanisms of fraxinellone, a degraded limonoid isolated from the root bark of Dictamnus dasycarpus, in the treatment of intestinal fibrosis.
[Acta Pharmacologica Sinica]
Abstract