Highly Multiplexed Spatial Analysis Identifies Tissue-Resident Memory T Cells as Drivers of Ulcerative and Immune Checkpoint Inhibitor Induced Colitis

Investigators showed that intra-epithelial CD8+ T cells were significantly more abundant in anti-PD-1 ± anti-CTLA-4-induced colitis compared to anti-CTLA-4-induced colitis and ulcerative colitis.