Chitosan Hydrogels with MK2 Inhibitor Peptide-Loaded Nanoparticles to Treat Atopic Dermatitis

A cell-penetrating mitogen-activated protein kinase–activated protein kinase-2 (MK2) inhibitor peptide YARA was loaded into hollow thermo-responsive pNIPAM nanoparticles, which were further incorporated into chitosan hydrogels to promote local drug delivery, improve moisture and the anti-inflammatory activity.
[Journal of Controlled Release]
AbstractGraphical Abstract

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