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e.g. organoids

MATR3 Is an Endogenous Inhibitor of DUX4 in FSHD Muscular Dystrophy

The authors identified Matrin 3 (MATR3), whose mutation caused amyotrophic lateral sclerosis and dominant distal myopathy, as a cellular factor controlling double homeobox 4 (DUX4) expression and activity.
[Cell Reports]
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