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e.g. organoids

KMT2A Associates with PHF5A-PHF14-HMG20A-RAI1 Subcomplex in Pancreatic Cancer Stem Cells and Epigenetically Regulates Their Characteristics

Targeting the protein subcomplex in pancreatic cancer stem cells with a KMT2A-WDR5 inhibitor attenuated their self-renewal capacity, cell viability, and in vivo tumorigenicity.
[Nature Communications]
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