Epigenomic Analysis Reveals a Unique DNA Methylation Program of Metastasis-Competent Circulating Tumor Cells in Colorectal Cancer

Researchers characterized the DNA methylation profile of metastasis-competent circulating tumor cells in colorectal cancer (CRC). The DNA methylome of the human CRC-derived cell line CTC-MCC-41 was analyzed and compared with primary and metastatic CRC cells.