Vascular Smooth Muscle Cells Enhance Immune/Vascular Interplay in a 3-Cell Model of Vascular Inflammation

Investigators determined the importance of vascular smooth muscle cells for shaping the extracellular cytokine/chemokine profile and transcriptional responses of vascular endothelial cellsto activated lipopolysaccharide-stimulated THP1 macrophages, in a 3-cell model of human vascular inflammation.