NewslettersImmune Regulation NewsTLR9 Ligand Sequestration by Chemokine CXCL4 Negatively Affects Central B Cell ToleranceBy Laurisa Dohm - October 6, 20230356The authors showed that CXCL4, a chemokine involved in systemic sclerosis, abrogated TLR9 function in B cells by sequestering TLR9 ligands away from the endosomal compartments where this receptor resides.[Journal Of Experimental Medicine]Abstract