SYVN1-Mediated Ubiquitylation Directs Localization of MCT4 in the Plasma Membrane to Promote the Progression of Lung Adenocarcinoma

Taking advantage of human lung adenocarcinoma cells, researchers revealed that MCT4 can be polyubiquitylated in a nonproteolytic manner by SYVN1 E3 ubiquitin ligase.