Glycyl-tRNA Synthetase Induces Psoriasis-Like Skin by Facilitating Skin Inflammation and Vascular Endothelial Cell Angiogenesis

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Glycyl-tRNA synthetase (GARS) was highly expressed in human skin keratinocytes, and GARS knockdown in keratinocytes suppressed cell proliferation and promoted apoptosis via the nuclear factor kappa-B/mitogen-activated protein kinase signaling pathway.
[Journal Of Investigative Dermatology]
AbstractGraphical Abstract