Chimeric Autoantibody Receptor T Cells Deplete NMDA Receptor-Specific B Cells

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Anti-NMDA receptor (NMDAR)-specific chimeric autoantibody receptor T cells recognized a large panel of human patient-derived autoantibodies, released effector molecules, proliferated, and selectively killed antigen-specific target cell lines even in the presence of high autoantibody concentrations.
[Cell]
AbstractGraphical Abstract