PD-1 Signaling Negatively Regulates the Common Cytokine Receptor γ Chain via MARCH5-Mediated Ubiquitination and Degradation to Suppress Anti-Tumor Immunity

By
Noshin Noorjahan
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Scientists showed that PD-1 ligation resulted in BATF-dependent transcriptional induction of the membrane-associated E3 ubiquitin ligase MARCH5.
[Cell Research]
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