NewslettersImmune Regulation NewsTarget ssDNA Activates the NADase Activity of Prokaryotic SPARTA Immune SystemBy Noshin Noorjahan - November 6, 2023043Researchers used cryo-electron microscopy to determine the structures of inactive monomeric and active tetrameric Crenotalea thermophila short prokaryotic Ago/TIR–APAZ (SPARTA) complexes.[Nature Chemical Biology]AbstractGraphical Abstract