Induced Pluripotent Stem Cells-Based Disease Modeling, Drug Screening, Clinical Trials, and Reverse Translational Research for Amyotrophic Lateral Sclerosis

For amyotrophic lateral sclerosis, a devastating neurodegenerative disease, several groups have identified candidate drugs, ezogabine, bosutinib, and ropinirole, using iPSCs-based drug discovery, and clinical trials using these drugs have been conducted, yielding interesting results.
[Journal Of Neurochemistry]
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