Recent Advances in Lung Organoid Development and Applications in Disease Modeling
The authors summarize the latest developments in lung organoid technology and their applicability for disease modeling and outline their strengths, drawbacks, and potential avenues for future development.
[Biogerontology] Investigators explored the possibility of inducing aging-associated features in cell types of the central nervous system using hiPSC technology.
[Journal Of Neuroscience] The authors reported using human tumor specimens and primary spheroids from male and female patients that GlialCAM, was differentially expressed in subpopulations of glioblastoma cells.
[Molecular Psychiatry] Investigators showed that the PTENG132D allele disrupted early neuroectoderm formation during the first several days of organoid generation, and results in deficient electrophysiology.