Age-Associated H3K9me2 Loss Alters the Regenerative Equilibrium between Murine Lung Alveolar and Bronchiolar Progenitors

Investigators reported that histone H3 lysine 9 di-methylation (H3K9me2), mediated by the methyltransferase G9a, regulated the dynamics of distal lung epithelial progenitor cells and that this regulation deteriorated with age.