TRPV4 Blockade Alleviates Endoplasmic Reticulum Stress Mediated Apoptosis in Hypoxia–Induced Cardiomyocyte Injury

The ability of transient receptor potential vanilloid 4 (TRPV4) to modulate the endoplasmic reticulum stress and apoptosis was assessed in vitro through the administration of the TRPV4 antagonist HC-067047 or the agonist GSK1016790A.